An estimated 70,000 adults suffering from sickle cell anemia may find relief through bone marrow transplants, according to recent news reports.
A team from the National Institutes of Health and Johns Hopkins University reported in the New England Journal of Medicine that it has developed a transplant procedure and used it to cure nine of the first 10 patients studied. About 200 children have been cured of sickle cell with transplants, but the procedure was too harsh for adults with severe cases of the disease. But the new procedure is less toxic.
"The main problem is that not enough sickle cell patients have a healthy sibling who is a compatible donor,'' an article in the Chicago Tribune reports. "A sibling donor is normally necessary in sickle-cell transplants to ensure that the patient doesn't reject the new marrow. The team plans to try using unrelated donors and parents.''
In the Unite States, approximately 2 million Americans, or 1 in 12 African American Americans, carry the sickle cell trait, according to Black Health Care.com. Furthermore, the disease occurs in 1 in every 500 African American births and 1 in every 1,000 to 1,400 Hispanic American births.
The disease is caused by a defective gene that tells the body to make abnormal hemoglobin, which result in deformed red blood cells. Symptoms include fatigue, pain in organs or joints, blindness, stroke, and acute chest pain.
Comments: (14)
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By: jeromequigley on 12/16/2009 11:39AM
Ms. Lynette Holloway: you should also look into a much better solution that is being prepared for testing right now. You can research the information about the work that is being done at the Cincinnati Childrens Hospital. They have found a way to take the blood of the person w/sickle cell and inject it with a dna(gene) that changes the dna make up to make the cells go round. Then once it generates in the sample they pull from the patient they inject it back into the patient and it goes to work on the rest of the blood!! It is amazing work because this way there is no need for a donor or All the complications and delays that it causes. So you really should keep on top of that work because if succesful this would be such a huge impact on any one w/sickle cell!! I really appreciat seeing articles that are meant to help people and not pull them apart and divide us as a country. Too many focus on race issues that tear our country apart by the way they go about it. We all need to have each others back! Pleas keep up the good work!!!!
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By: vincint on 12/22/2009 7:15PM
Without further thought look at Dr. Sebi on you tube for a cure.
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By: Tina on 12/16/2009 9:40PM
Hello Ms. Lynette Holloway,
My daughter has sickle cell, stage(SC). My husband and I read the article and found it interesting and would like more information. We are interested in the transplant and what steps we need to take to make this possible for our daughter.
Thank you very much for the information , it was greatly appreciated.
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By: Cindy on 12/17/2009 7:25PM
Actually my mother had this disease and having others like diabetes kind of affected her from being able to survive it longer and she passed leaving my brother and I practically babies. Reading this article makes me filled with joy because it helps understand that research is being done on it to help those who are currently suffering. Especially the younger children, I see them alot in the medical field and brings tears to my eyes to see them suffer. I may have the trait but it's not the same. I hope your daughter is aable to get this transplant, I pray that you get the assistance in getting her better. Good Luck!!
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By: vincint on 12/22/2009 7:16PM
please see Dr.Sebi on you tube for a cure.
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By: Sister Naomi on 12/21/2009 9:12PM
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By: vincint on 12/22/2009 7:16PM
Dr. Sebi on you tube please.
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